Fatigue remains a major symptom encountered in Sjögren’s Syndrome, and this phenomenon has already been documented in quite a number of studies. A recent Dutch study (published in this month’s Annals of the Rheumatic Diseases) adds to that series and suggests that fatigue in patients with Sjögren’s syndrome might be reduced by targeting both physical activity and physical activity cognitions.
Find a link to the abstract here.
A recently published thesis by Nienke Roescher from the University of Amsterdam further contributes to the difficult and ongoing search on how to tackle the disease Sjögrenś sydnrome. Although as a rheumatologist I am more into clinical research, the evolving knowledge obtained from basic (laboratory) research is of invaluable importance in guiding the way to find a cure for this disease.
Nienke Roescher concluded her thesis as follows:
The research presented herein summarizes the current knowledge on cytokines and their presence in SS, it identifies immunological targets in mice with an SS-like disease and shows that local gene therapy can be successful for the treatment of the inflammatory salivary gland component of a SS-like disorder in mice. The chance for success of this approach depends on proper timing and should be aimed at the right target.
American College of Rheumatology classification criteria for Sjögren’s syndrome: A data-driven, expert consensus approach in the Sjögren’s International Collaborative Clinical Alliance Cohort – Shiboski – 2012 – Arthritis Care & Research – Wiley Online Library
American College of Rheumatology classification criteria for Sjögren's syndrome: A data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance Cohort – Shiboski – 2012 – Arthritis Care & Research – Wiley Online Library.
(thanks @AmiDauhoo for notifying me)