Posts Tagged ‘disease activity’

PARA study Rotterdam: >10 years of research on RA and pregnancy

26 September 2015 Leave a comment

The annual 2-day conference of the Dutch Rheumatology Association (NVR) took place last week. One of the invited speakers was Dr RJEM Dolhain (photo) from Erasmus University Medical Center, Rotterdam, the Netherlands. Dr Dolhain provided the audience with a nice overview of what over a decade of research (in the so-called PARA study 2002-2015) in rheumatoid arthritis and pregnancy has yielded so far. The Rotterdam PARA study can be considered as the world’s largest (and ongoing) study of pregnancy related topics in rheumatoid arthritis (follow-up of n=300 of which 250 women have become pregnant). The highlights (i.e. from my own notes during his excellent talk) are listed in this blogpost. Read more…

Meeting report (part 4b): evaluating muscle function in inflammatory myopathies

1 February 2012 Leave a comment

Advances in basic experimental as well as clinical research on pathophysiological mechanisms and treatment opportunities of various rheumatoid disease conditions have been complicated or frustrated by issues like how to define a disease (i.e. proper diagnosis) and how to define measurement of treatment response (i.e. which outcome measuers should be targeted and evaluated in trials). In this blog, after putting things in a broader context shortly, I will write what I learned about evaluating disease activity of inflammatory myopathies in daily clinical practise, and to be more precise evaluating muscle functioning. Two standardised examinations are available for that purpose: the MMT-8 and the FI-2. Read more…


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